Cimel™ is developed and manufactured by EXPERTISSE and INNOAESTHETICS laboratories in Barcelona, Spain, in partnership with medical cosmetic expert Dr. Fernando Bouffard, Ph.D., CEO of EXPERTISSE Labs. The brand is a registered trademark of Derma Beauty Inc., which also serves as the exclusive agent for North America. Internationally, cimel™ is distributed and represented by partners such as Diamond Vision, alongside sister brands Hyalual Institute, Meditopic, Alpha Genera, Exocleo, and Italfarmacia.
Cold peel
Cimel™ is a professional-grade, evidence-based cosmetic peel and skincare line marketed as “the most safe and effective cold peel.” It delivers the results of a chemical peel without the harsh chemical burn — a gentle, self-neutralizing, in-clinic “cold” activator paired with a full homecare system.
Hyperpigmentation — from sun exposure, post-inflammatory hyperpigmentation (PIH), hormonal changes (melasma), or genetic predisposition — affects a large share of the population and can take a real emotional toll on quality of life.
Our amazing team is always hard at work
Unlike traditional single-acid peels that act at only one stage of melanin production, cimel™ is built on a multi-active formula that targets several stages of the melanogenesis pathway at once — from the melanocyte and α-MSH signal, through adenylate cyclase and protein kinase A, to the tyrosinase enzyme itself. This multi-target approach is designed to deliver stronger clinical results than any single-ingredient compound, backed by findings recognized by the American Academy of Dermatology (AAD).
Key Ingredient Categories
Peeling Agents
Salicylic Acid (BHA exfoliant, fades PIH); Cyclodextrin-stabilized Retinol (cell turnover, reduces pigmentation and fine lines)
Tyrosinase Inhibitors
Alpha Arbutin, Kojic Acid (reduce melanin production, fade dark spots and melasma)
Antioxidants
Tocopherol / Vitamin E; Phyllanthus Emblica (Amla) Extract (fights free radicals, protects from UV and pollution stress)
Anti-Inflammatory Agents
Arnica Montana, Glycyrrhetinic Acid, Cupressus Sempervirens Seed Extract (calm redness and irritation)
Skin-Soothing Agents
Polygonatum Multiflorum Extract (hydration and texture improvement)
Clinical Results
Independent clinical study data (Cisneros, Del Rio & Bouffard, “Innovation in Peelings: Cimel, with Depigmenting & Rejuvenating Action,” Medicina Cutánea Ibero-Latino-Americana, 2003 — 183 patients, Fitzpatrick II–V, 5-month cohort study) showed improvement in:
